Version 5.4
Homo sapiens Gene: TPST2
Summary
InnateDB Gene IDBG-3215.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPST2
Gene Name tyrosylprotein sulfotransferase 2
Synonyms TANGO13B
Species Homo sapiens
Ensembl Gene ENSG00000128294
Encoded Proteins
IDBP-3217
tyrosylprotein sulfotransferase 2
IDBP-233835
tyrosylprotein sulfotransferase 2
IDBP-294858
tyrosylprotein sulfotransferase 2
IDBP-368934
tyrosylprotein sulfotransferase 2
IDBP-368936
tyrosylprotein sulfotransferase 2
IDBP-368938
tyrosylprotein sulfotransferase 2
IDBP-368939
tyrosylprotein sulfotransferase 2
IDBP-368940
tyrosylprotein sulfotransferase 2
IDBP-368942
tyrosylprotein sulfotransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:26525492-26596717
Strand Reverse strand
Band q12.1
Transcripts
ENST00000338754 ENSP00000339813
ENST00000398110 ENSP00000381180
ENST00000403880 ENSP00000385192
ENST00000445720 ENSP00000403758
ENST00000442495 ENSP00000403875
ENST00000454778 ENSP00000400357
ENST00000440953 ENSP00000416791
ENST00000453117 ENSP00000401134
ENST00000450022 ENSP00000414809
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation
GO:0007342 fusion of sperm to egg plasma membrane
GO:0060468 prevention of polyspermy
Cellular Component
GO:0000139 Golgi membrane
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029344
View Gene Order
ENSBTAG00000010368
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001008566 NM_003595 XM_006724338
HUGO
OMIM
CCDS CCDS13839
HPRD 07217
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca