Version 5.4
Homo sapiens Gene: MICAL2
Summary
InnateDB Gene IDBG-32315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MICAL2
Gene Name microtubule associated monoxygenase, calponin and LIM domain containing 2
Synonyms MICAL-2; MICAL2PV1; MICAL2PV2
Species Homo sapiens
Ensembl Gene ENSG00000133816
Encoded Proteins
IDBP-32319
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-32321
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-32323
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-583526
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-594322
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-597380
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-590215
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-595742
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-602450
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-587605
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-600724
microtubule associated monoxygenase, calponin and LIM domain containing 2
IDBP-587164
microtubule associated monoxygenase, calponin and LIM domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:12094008-12263789
Strand Forward strand
Band p15.3
Transcripts
ENST00000256194 ENSP00000256194
ENST00000379612 ENSP00000368932
ENST00000342902 ENSP00000344894
ENST00000532179 ENSP00000434209
ENST00000526065 ENSP00000435270
ENST00000532945
ENST00000531732
ENST00000530823 ENSP00000434957
ENST00000532420 ENSP00000433818
ENST00000527546 ENSP00000433965
ENST00000524685 ENSP00000437229
ENST00000525119 ENSP00000433509
ENST00000533389 ENSP00000433357
ENST00000528931
ENST00000532166
ENST00000527195
ENST00000530691
ENST00000524730
ENST00000533219
ENST00000529562
ENST00000526475
ENST00000525075
ENST00000525216
ENST00000534563
ENST00000525979
ENST00000526672
ENST00000525618
ENST00000530021
ENST00000526604
ENST00000525444
ENST00000537344 ENSP00000441689
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0043914 NADPH:sulfur oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0001947 heart looping
GO:0007010 cytoskeleton organization
GO:0007507 heart development
GO:0010735 positive regulation of transcription via serum response element binding
GO:0019417 sulfur oxidation
GO:0030042 actin filament depolymerization
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038244
View Gene Order
ENSBTAG00000014855
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.501928 Hs.621916 Hs.627793 Hs.735627
RefSeq NM_001282663 NM_001282664 NM_001282665 NM_001282666 NM_001282667 NM_014632 XM_005253249
HUGO
OMIM
CCDS CCDS60726 CCDS60727 CCDS60728 CCDS7809
HPRD 10085
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca