Version 5.4
Homo sapiens Gene: PLD6
Summary
InnateDB Gene IDBG-32726.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLD6
Gene Name phospholipase D family, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000179598
Encoded Proteins
IDBP-32728
phospholipase D family, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:17200995-17206315
Strand Reverse strand
Band p11.2
Transcripts
ENST00000321560 ENSP00000317177
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004519 endonuclease activity
GO:0035755 cardiolipin hydrolase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006655 phosphatidylglycerol biosynthetic process
GO:0007126 meiotic nuclear division
GO:0007286 spermatid development
GO:0008053 mitochondrial fusion
GO:0008152 metabolic process
GO:0016042 lipid catabolic process
GO:0030719 P granule organization
GO:0034587 piRNA metabolic process
GO:0043046 DNA methylation involved in gamete generation
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005741 mitochondrial outer membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043648
View Gene Order
ENSBTAG00000008009
Not yet available
Pathways
NETPATH
REACTOME
REACT_121280
Synthesis of PG pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8N2A8
TrEMBL
UniProt Splice Variant
Entrez Gene 201164
UniGene Hs.729079
RefSeq NM_178836
HUGO HGNC:30447
OMIM 614960
CCDS CCDS11182
HPRD
IMGT
EMBL AC055811 AK090899 BC031263
GenPept AAH31263 BAC03541
RNA Seq Atlas 201164

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca