Homo sapiens Gene: COPB1
Summary
InnateDB Gene IDBG-33088.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPB1
Gene Name coatomer protein complex, subunit beta 1
Synonyms COPB;
Species Homo sapiens
Ensembl Gene ENSG00000129083
Encoded Proteins
coatomer protein complex, subunit beta 1
coatomer protein complex, subunit beta 1
coatomer protein complex, subunit beta 1
coatomer protein complex, subunit beta 1
coatomer protein complex, subunit beta 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein subunit of the coatomer complex associated with non-clathrin coated vesicles. The coatomer complex, also known as the coat protein complex 1, forms in the cytoplasm and is recruited to the Golgi by activated guanosine triphosphatases. Once at the Golgi membrane, the coatomer complex may assist in the movement of protein and lipid components back to the endoplasmic reticulum. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:14443440-14500027
Strand Reverse strand
Band p15.2
Transcripts
ENST00000249923 ENSP00000249923
ENST00000439561 ENSP00000397873
ENST00000532088
ENST00000525214
ENST00000526527
ENST00000526191
ENST00000534234 ENSP00000436383
ENST00000529866 ENSP00000431530
ENST00000534771 ENSP00000436401
ENST00000533096
ENST00000533533
ENST00000529210
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 88 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 88 [view]
Protein-Protein 87 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0016032 viral process
GO:0016192 vesicle-mediated transport
GO:0048205 COPI coating of Golgi vesicle
GO:0061024 membrane organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0005798 Golgi-associated vesicle
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030117 membrane coat
GO:0030126 COPI vesicle coat
GO:0030137 COPI-coated vesicle
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
COPI Mediated Transport pathway
Golgi to ER Retrograde Transport pathway
Membrane Trafficking pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.339278 Hs.619340 Hs.733091
RefSeq NM_001144061 NM_001144062 NM_016451
HUGO
OMIM
CCDS CCDS7815
HPRD 02981
IMGT
EMBL
GenPept
RNA Seq Atlas