Version 5.4
Homo sapiens Gene: MOGAT3
Summary
InnateDB Gene IDBG-33097.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MOGAT3
Gene Name monoacylglycerol O-acyltransferase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106384
Encoded Proteins
IDBP-33099
monoacylglycerol O-acyltransferase 3
IDBP-33101
monoacylglycerol O-acyltransferase 3
IDBP-384152
monoacylglycerol O-acyltransferase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:101195007-101201021
Strand Reverse strand
Band q22.1
Transcripts
ENST00000223114 ENSP00000223114
ENST00000379423 ENSP00000368734
ENST00000440203 ENSP00000403756
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0004144 diacylglycerol O-acyltransferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006071 glycerol metabolic process
GO:0019432 triglyceride biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa00561
Glycerolipid metabolism pathway
hsa04975
Fat digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q86VF5
TrEMBL
UniProt Splice Variant
Entrez Gene 346606
UniGene Hs.512217
RefSeq NM_001287147 NM_178176 XM_005250309
HUGO HGNC:23249
OMIM 610184
CCDS CCDS5714 CCDS75643
HPRD
IMGT
EMBL AC004876 AY229854 AY358200 BC100953 BC100954 BC100955
GenPept AAD45832 AAI00954 AAI00955 AAI00956 AAO63579 AAQ88567
RNA Seq Atlas 346606

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca