Version 5.4
Homo sapiens Gene: DOK4
Summary
InnateDB Gene IDBG-33376.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DOK4
Gene Name docking protein 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125170
Encoded Proteins
IDBP-33378
docking protein 4
IDBP-749774
IDBP-750128
IDBP-752507
IDBP-752685
IDBP-754427
IDBP-753932
IDBP-748725
IDBP-748243
IDBP-749481
IDBP-745144
IDBP-753511
IDBP-752579
IDBP-753210
IDBP-747384
IDBP-753606
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:57471922-57487327
Strand Reverse strand
Band q21
Transcripts
ENST00000340099 ENSP00000344277
ENST00000562737 ENSP00000457621
ENST00000566936 ENSP00000455566
ENST00000566588 ENSP00000457670
ENST00000567175 ENSP00000455528
ENST00000569010 ENSP00000457971
ENST00000569250 ENSP00000456590
ENST00000561918
ENST00000562008 ENSP00000457188
ENST00000569538 ENSP00000456739
ENST00000566705 ENSP00000454738
ENST00000568617 ENSP00000457192
ENST00000569548 ENSP00000455128
ENST00000561659 ENSP00000456864
ENST00000567214 ENSP00000457212
ENST00000564378 ENSP00000458037
ENST00000567276 ENSP00000457730
ENST00000563483
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
Biological Process
GO:0000165 MAPK cascade
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 nervous system development
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000040631
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000001857
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
ret_pathway
Signaling events regulated by Ret tyrosine kinase
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.279832
RefSeq NM_018110 XM_005256042 XM_005256043
HUGO
OMIM
CCDS CCDS10783
HPRD 16316
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca