Version 5.4
Homo sapiens Gene: TTC37
Summary
InnateDB Gene IDBG-33633.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TTC37
Gene Name tetratricopeptide repeat domain 37
Synonyms KIAA0372; Ski3
Species Homo sapiens
Ensembl Gene ENSG00000198677
Encoded Proteins
IDBP-33637
tetratricopeptide repeat domain 37
IDBP-477934
tetratricopeptide repeat domain 37
IDBP-483436
tetratricopeptide repeat domain 37
IDBP-480038
tetratricopeptide repeat domain 37
IDBP-484320
tetratricopeptide repeat domain 37
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with twenty tetratricopeptide (TPR) repeats. Tetratricopeptide repeat containing motifs are found in a variety of proteins and may mediate protein-protein interactions and chaperone activity. Mutations in this gene are associated with trichohepatoenteric syndrome. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:95463895-95555007
Strand Reverse strand
Band q15
Transcripts
ENST00000358746 ENSP00000351596
ENST00000502768
ENST00000508181
ENST00000512026
ENST00000515176
ENST00000507805
ENST00000506007
ENST00000513232 ENSP00000422749
ENST00000505578 ENSP00000423141
ENST00000514952 ENSP00000423742
ENST00000504421
ENST00000503279
ENST00000515207
ENST00000513823 ENSP00000425403
ENST00000510228
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0035327 transcriptionally active chromatin
GO:0055087 Ski complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033991
View Gene Order
ENSBTAG00000009131
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.482868
RefSeq NM_014639
HUGO
OMIM
CCDS CCDS4072
HPRD 11079
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca