Version 5.4
Homo sapiens Gene: NOV
Summary
InnateDB Gene IDBG-33777.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NOV
Gene Name nephroblastoma overexpressed
Synonyms CCN3; IBP-9; IGFBP-9; IGFBP9; NOVh
Species Homo sapiens
Ensembl Gene ENSG00000136999
Encoded Proteins
IDBP-33779
nephroblastoma overexpressed gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:119416306-119424353
Strand Forward strand
Band q24.12
Transcripts
ENST00000259526 ENSP00000259526
ENST00000520082
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0008083 growth factor activity
Biological Process
GO:0001558 regulation of cell growth
GO:0010468 regulation of gene expression
Cellular Component
GO:0005576 extracellular region
GO:0030424 axon
GO:0030425 dendrite
GO:0031012 extracellular matrix
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037362
View Gene Order
ENSBTAG00000002080
Not yet available
Pathways
NETPATH
NetPath_3
Notch pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt P48745
TrEMBL A0A024R9J4 B3FHX2
UniProt Splice Variant
Entrez Gene 4856
UniGene Hs.235935
RefSeq NM_002514
HUGO HGNC:7885
OMIM 164958
CCDS CCDS6328
HPRD
IMGT
EMBL AK312355 AY082381 BC015028 CH471060 CR457432 EU118751 X78351 X78352 X78353 X78354 X96584
GenPept AAH15028 AAL92490 ABW90714 BAG35274 CAA55146 CAA65403 CAG33713 EAW91984 EAW91985
RNA Seq Atlas 4856

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca