Homo sapiens Gene: GINS3
Summary
InnateDB Gene IDBG-34261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GINS3
Gene Name GINS complex subunit 3 (Psf3 homolog)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181938
Encoded Proteins
GINS complex subunit 3 (Psf3 homolog)
GINS complex subunit 3 (Psf3 homolog)
GINS complex subunit 3 (Psf3 homolog)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:58295080-58406144
Strand Forward strand
Band q21
Transcripts
ENST00000318129 ENSP00000318196
ENST00000328514 ENSP00000327449
ENST00000426538 ENSP00000401018
ENST00000561952
ENST00000567143
ENST00000568468
ENST00000564814
ENST00000567400
ENST00000567909
ENST00000567432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9BRX5
TrEMBL
UniProt Splice Variant
Entrez Gene 64785
UniGene Hs.47125
RefSeq NM_001126129 NM_001126130 NM_022770
HUGO HGNC:25851
OMIM 610610
CCDS CCDS45498 CCDS10796 CCDS45499
HPRD 07842
IMGT
EMBL AC009107 AC009118 AC084063 AK023974 AK315622 BC005879 BC014437 CH471092 CR457283
GenPept AAH05879 AAH14437 BAB14747 BAG37990 CAG33564 EAW82973 EAW82976
RNA Seq Atlas 64785