Version 5.4
Homo sapiens Gene: GINS3
Summary
InnateDB Gene IDBG-34261.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GINS3
Gene Name GINS complex subunit 3 (Psf3 homolog)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181938
Encoded Proteins
IDBP-34265
GINS complex subunit 3 (Psf3 homolog)
IDBP-34267
GINS complex subunit 3 (Psf3 homolog)
IDBP-378079
GINS complex subunit 3 (Psf3 homolog)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:58295080-58406144
Strand Forward strand
Band q21
Transcripts
ENST00000318129 ENSP00000318196
ENST00000328514 ENSP00000327449
ENST00000426538 ENSP00000401018
ENST00000561952
ENST00000567143
ENST00000568468
ENST00000564814
ENST00000567400
ENST00000567909
ENST00000567432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 29 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031669
View Gene Order
ENSBTAG00000009363
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.47125
RefSeq NM_001126129 NM_001126130 NM_022770
HUGO
OMIM
CCDS CCDS10796 CCDS45498 CCDS45499
HPRD 07842
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca