InnateDB Protein
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IDBP-34265.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GINS3
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Protein Name
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GINS complex subunit 3 (Psf3 homolog)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000318196
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InnateDB Gene
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IDBG-34261 (GINS3)
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Protein Structure
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Function |
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. {ECO:0000269PubMed:17417653}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
30
[view]
|
Protein-Protein |
29
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR021151
GINS complex
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PFAM |
PF05916
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BRX5
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PhosphoSite |
PhosphoSite-Q9BRX5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
64785
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UniGene |
Hs.47125
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RefSeq |
NP_073607
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HUGO |
HGNC:25851
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OMIM |
610610
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CCDS |
CCDS10796
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HPRD |
07842
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IMGT |
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EMBL |
AC009107
AC009118
AC084063
AK023974
AK315622
BC005879
BC014437
CH471092
CR457283
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GenPept |
AAH05879
AAH14437
BAB14747
BAG37990
CAG33564
EAW82973
EAW82976
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