InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CYP4F22

Summary

InnateDB Gene

IDBG-34782.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP4F22

Gene Name

cytochrome P450, family 4, subfamily F, polypeptide 22

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000171954

Encoded Proteins

IDBP-34784

cytochrome P450, family 4, subfamily F, polypeptide 22

IDBP-761774

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:15508493-15552317

Strand

Forward strand

Band

p13.12

Transcripts

ENST00000269703	ENSP00000269703
ENST00000601005	ENSP00000469866

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding