Bos taurus Gene: CYP4F22
Summary
InnateDB Gene IDBG-642405.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP4F22
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000047933
Encoded Proteins
cytochrome P450, family 4, subfamily F, polypeptide 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171954:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:8629102-8651746
Strand Reverse strand
Band
Transcripts
ENSBTAT00000066325 ENSBTAP00000055004
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016491 oxidoreductase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0055114 oxidation-reduction process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of lipids and lipoproteins pathway
Arachidonic acid metabolism pathway
Cytochrome P450 - arranged by substrate type pathway
Synthesis of Leukotrienes (LT) and Eoxins (EX) pathway
Fatty acids pathway
Metabolism pathway
Biological oxidations pathway
Eicosanoids pathway
Miscellaneous substrates pathway
Phase 1 - Functionalization of compounds pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL G3MZK4
UniProt Splice Variant
Entrez Gene 100301224
UniGene
RefSeq XM_002688557 XM_003582371 XM_005192345 XM_005208570
HUGO HGNC:26820
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02019128 DAAA02019129 DAAA02019130
GenPept
RNA Seq Atlas 100301224