Homo sapiens Gene: TRMT12
Summary
InnateDB Gene IDBG-34958.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRMT12
Gene Name tRNA methyltransferase 12 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000183665
Encoded Proteins
tRNA methyltransferase 12 homolog (S. cerevisiae)
tRNA methyltransferase 12 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:124450820-124462150
Strand Forward strand
Band q24.13
Transcripts
ENST00000328599 ENSP00000329858
ENST00000521443
ENST00000522518 ENSP00000429771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 0
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016740 transferase activity
Biological Process
GO:0008033 tRNA processing
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q53H54
TrEMBL
UniProt Splice Variant
Entrez Gene 55039
UniGene Hs.711325 Hs.9925
RefSeq NM_017956
HUGO HGNC:26091
OMIM 611244
CCDS CCDS6349
HPRD 07947
IMGT
EMBL AK000779 AK222727 BC003057 BC011713
GenPept AAH03057 AAH11713 BAA91374 BAD96447
RNA Seq Atlas 55039