Homo sapiens Gene: NSMCE2
Summary
InnateDB Gene IDBG-35364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NSMCE2
Gene Name non-SMC element 2, MMS21 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000156831
Encoded Proteins
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
non-SMC element 2, MMS21 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 8:125091679-125367120
Strand Forward strand
Band q24.13
Transcripts
ENST00000287437 ENSP00000287437
ENST00000523741 ENSP00000429383
ENST00000520866 ENSP00000478256
ENST00000519010 ENSP00000481615
ENST00000517532 ENSP00000429612
ENST00000518013 ENSP00000431002
ENST00000523824
ENST00000522563 ENSP00000430668
ENST00000518146 ENSP00000430313
ENST00000523549
ENST00000519712 ENSP00000429014
ENST00000517315 ENSP00000428846
ENST00000521460
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019789 SUMO ligase activity
Biological Process
GO:0000722 telomere maintenance via recombination
GO:0000724 double-strand break repair via homologous recombination
GO:0007067 mitotic nuclear division
GO:0016567 protein ubiquitination
GO:0016925 protein sumoylation
GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842 positive regulation of mitotic metaphase/anaphase transition
GO:0090398 cellular senescence
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0016605 PML body
GO:0030915 Smc5-Smc6 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL E5RFJ1
UniProt Splice Variant
Entrez Gene 286053
UniGene
RefSeq NM_173685 XM_005250875 XM_005250876
HUGO HGNC:26513
OMIM
CCDS CCDS6356
HPRD 08131
IMGT
EMBL AC084083 AC126366
GenPept
RNA Seq Atlas 286053