Version 5.4
Homo sapiens Protein: NSMCE2
Summary
InnateDB Protein IDBP-478489.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NSMCE2
Protein Name non-SMC element 2, MMS21 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000428846
InnateDB Gene IDBG-35364 (NSMCE2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
Experimentally validated
Total 24 [view]
Protein-Protein 24 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
GO:0019789 SUMO ligase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0030915 Smc5-Smc6 complex
Protein Structure and Domains
PDB ID
InterPro IPR003613 U box domain
IPR004181 Zinc finger, MIZ-type
PFAM PF04564
PF02891
PRINTS
PIRSF
SMART SM00504
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E5RFJ1
UniProt Splice Variant
Entrez Gene 286053
UniGene
RefSeq
HUGO HGNC:26513
OMIM
CCDS
HPRD 08131
IMGT
EMBL AC084083 AC126366
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca