Version 5.4
Homo sapiens Gene: CMTM3
Summary
InnateDB Gene IDBG-35390.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CMTM3
Gene Name CKLF-like MARVEL transmembrane domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140931
Encoded Proteins
IDBP-35394
CKLF-like MARVEL transmembrane domain containing 3
IDBP-378530
CKLF-like MARVEL transmembrane domain containing 3
IDBP-746899
IDBP-746136
IDBP-751229
IDBP-746903
IDBP-749322
IDBP-746619
IDBP-744763
IDBP-748928
IDBP-750232
IDBP-749811
IDBP-751132
IDBP-751614
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:66603874-66613892
Strand Forward strand
Band q22.1
Transcripts
ENST00000361909 ENSP00000354579
ENST00000424011 ENSP00000400482
ENST00000460097 ENSP00000461758
ENST00000562357 ENSP00000454628
ENST00000564060 ENSP00000457589
ENST00000564247
ENST00000566121 ENSP00000457923
ENST00000568477 ENSP00000461654
ENST00000565003 ENSP00000460330
ENST00000562707 ENSP00000455758
ENST00000567572 ENSP00000455851
ENST00000565666 ENSP00000462554
ENST00000565922 ENSP00000456426
ENST00000563672 ENSP00000457451
ENST00000566756 ENSP00000462613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005515 protein binding
Biological Process
GO:0006935 chemotaxis
GO:0050861 positive regulation of B cell receptor signaling pathway
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031965 nuclear membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031875
View Gene Order
ENSBTAG00000047654
Not yet available
Pathways
NETPATH
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.298198 Hs.736516
RefSeq NM_144601 NM_181553
HUGO
OMIM
CCDS CCDS10815
HPRD 16259
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca