Homo sapiens Gene: SEC24D
Summary
InnateDB Gene IDBG-35522.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC24D
Gene Name SEC24 family, member D (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000150961
Encoded Proteins
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
SEC24 family, member D (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:118722823-118838683
Strand Reverse strand
Band q26
Transcripts
ENST00000280551 ENSP00000280551
ENST00000419654 ENSP00000388324
ENST00000505134
ENST00000511481 ENSP00000425491
ENST00000502830
ENST00000511715
ENST00000514561 ENSP00000422717
ENST00000502526
ENST00000511033
ENST00000509818 ENSP00000424085
ENST00000514418
ENST00000506622 ENSP00000427249
ENST00000503683 ENSP00000426309
ENST00000505280
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008270 zinc ion binding
Biological Process
GO:0001701 in utero embryonic development
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0018279 protein N-linked glycosylation via asparagine
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044281 small molecule metabolic process
GO:0048208 COPII vesicle coating
GO:0061024 membrane organization
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0012507 ER to Golgi transport vesicle membrane
GO:0030127 COPII vesicle coat
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
MHC class II antigen presentation pathway
Metabolism of lipids and lipoproteins pathway
Post-translational protein modification pathway
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
ER to Golgi Transport pathway
Asparagine N-linked glycosylation pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
Class I MHC mediated antigen processing & presentation pathway
Metabolism pathway
Membrane Trafficking pathway
Transport to the Golgi and subsequent modification pathway
KEGG
Protein processing in endoplasmic reticulum pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL D6RAE2
UniProt Splice Variant
Entrez Gene 9871
UniGene Hs.189641 Hs.594121 Hs.617443 Hs.692848
RefSeq NM_014822 XM_005263379 XM_005263378
HUGO HGNC:10706
OMIM 607186
CCDS CCDS3710
HPRD 06218
IMGT
EMBL AC108030 AC110079
GenPept
RNA Seq Atlas 9871