InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: IFT20

Summary

InnateDB Gene

IDBG-36364.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IFT20

Gene Name

intraflagellar transport 20 homolog (Chlamydomonas)

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000109083

Encoded Proteins

IDBP-36366

intraflagellar transport 20 homolog (Chlamydomonas)

IDBP-239585

intraflagellar transport 20 homolog (Chlamydomonas)

IDBP-761732

IDBP-763199

IDBP-760332

IDBP-757899

IDBP-758469

IDBP-761740

IDBP-758733

IDBP-809851

intraflagellar transport 20

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:28328325-28335489

Strand

Reverse strand

Band

q11.2

Transcripts

ENST00000357896	ENSP00000350570
ENST00000322326
ENST00000395418	ENSP00000378809
ENST00000578122	ENSP00000464147
ENST00000578985	ENSP00000464033
ENST00000578009	ENSP00000464210
ENST00000580991
ENST00000585089	ENSP00000464443
ENST00000578547
ENST00000577498	ENSP00000462163
ENST00000580357
ENST00000585313	ENSP00000463138
ENST00000579419	ENSP00000463322
ENST00000583796
ENST00000582797
ENST00000588477	ENSP00000484842

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	14 [view]
Protein-Protein	14 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002046	opsin binding
GO:0005515	protein binding

Biological Process

GO:0001822	kidney development
GO:0007224	smoothened signaling pathway
GO:0008542	visual learning
GO:0022008	neurogenesis
GO:0034067	protein localization to Golgi apparatus
GO:0035845	photoreceptor cell outer segment organization
GO:0036372	opsin transport
GO:0042384	cilium assembly
GO:0051642	centrosome localization
GO:0055007	cardiac muscle cell differentiation
GO:0060828	regulation of canonical Wnt signaling pathway
GO:0061351	neural precursor cell proliferation
GO:0061512	protein localization to cilium
GO:1902017	regulation of cilium assembly
GO:2000785	regulation of autophagic vacuole assembly

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005814	centriole
GO:0005929	cilium
GO:0030992	intraciliary transport particle B
GO:0031514	motile cilium
GO:0032391	photoreceptor connecting cilium
GO:0036064	ciliary basal body
GO:0044292	dendrite terminus
GO:0070062	extracellular vesicular exosome
GO:0072372	primary cilium
GO:0097546	ciliary base

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000001105

View Gene Order

ENSBTAG00000008110

Not yet available

Cross-References

SwissProt

Q8IY31

TrEMBL

A0A024QZ08 J3KRU2 J3QR43

UniProt Splice Variant

Entrez Gene

90410

UniGene

Hs.609288 Hs.743256

RefSeq

NM_001267774 NM_001267775 NM_001267776 NM_001267777 NM_001267778 NM_174887

HUGO

HGNC:30989

OMIM

614394

CCDS

CCDS58535 CCDS32593 CCDS58533 CCDS58534 CCDS74017

HPRD

17137

IMGT

EMBL

AC002094 AY224601 BC002640 BC038094 BQ639919 CH471159

GenPept

AAH02640 AAH38094 AAP50265 EAW51072 EAW51076

RNA Seq Atlas

90410