Homo sapiens Gene: IFT20
Summary
InnateDB Gene IDBG-36364.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT20
Gene Name intraflagellar transport 20 homolog (Chlamydomonas)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000109083
Encoded Proteins
intraflagellar transport 20 homolog (Chlamydomonas)
intraflagellar transport 20 homolog (Chlamydomonas)
intraflagellar transport 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:28328325-28335489
Strand Reverse strand
Band q11.2
Transcripts
ENST00000357896 ENSP00000350570
ENST00000322326
ENST00000395418 ENSP00000378809
ENST00000578122 ENSP00000464147
ENST00000578985 ENSP00000464033
ENST00000578009 ENSP00000464210
ENST00000580991
ENST00000585089 ENSP00000464443
ENST00000578547
ENST00000577498 ENSP00000462163
ENST00000580357
ENST00000585313 ENSP00000463138
ENST00000579419 ENSP00000463322
ENST00000583796
ENST00000582797
ENST00000588477 ENSP00000484842
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002046 opsin binding
GO:0005515 protein binding
Biological Process
GO:0001822 kidney development
GO:0007224 smoothened signaling pathway
GO:0008542 visual learning
GO:0022008 neurogenesis
GO:0034067 protein localization to Golgi apparatus
GO:0035845 photoreceptor cell outer segment organization
GO:0036372 opsin transport
GO:0042384 cilium assembly
GO:0051642 centrosome localization
GO:0055007 cardiac muscle cell differentiation
GO:0060828 regulation of canonical Wnt signaling pathway
GO:0061351 neural precursor cell proliferation
GO:0061512 protein localization to cilium
GO:1902017 regulation of cilium assembly
GO:2000785 regulation of autophagic vacuole assembly
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005814 centriole
GO:0005929 cilium
GO:0030992 intraciliary transport particle B
GO:0031514 motile cilium
GO:0032391 photoreceptor connecting cilium
GO:0036064 ciliary basal body
GO:0044292 dendrite terminus
GO:0070062 extracellular vesicular exosome
GO:0072372 primary cilium
GO:0097546 ciliary base
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.609288 Hs.743256
RefSeq NM_001267774 NM_001267775 NM_001267776 NM_001267777 NM_001267778 NM_174887
HUGO
OMIM
CCDS CCDS32593 CCDS58533 CCDS58534 CCDS58535 CCDS74017
HPRD 17137
IMGT
EMBL
GenPept
RNA Seq Atlas