InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ift20

Summary

InnateDB Gene

IDBG-203058.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ift20

Gene Name

intraflagellar transport 20

Synonyms

0610009H04Rik; AU015496

Species

Mus musculus

Ensembl Gene

ENSMUSG00000001105

Encoded Proteins

IDBP-203060

intraflagellar transport 20 homolog (Chlamydomonas)

IDBP-264884

intraflagellar transport 20 homolog (Chlamydomonas)

IDBP-542315

intraflagellar transport 20 homolog (Chlamydomonas)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109083:
This gene encodes a intraflagellar transport protein important for intracellular transport. The encoded protein forms part of a complex involved in trafficking of proteins from the Golgi body, including recycling of immune signalling components (Finetti et al., PubMed: 19855387). This gene is part of a complex set of sense-antisense loci that may be co-regulated. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 14.[provided by RefSeq, Jun 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:78536361-78541737

Strand

Forward strand

Band

Transcripts

ENSMUST00000050366	ENSMUSP00000051699
ENSMUST00000108275	ENSMUSP00000103910
ENSMUST00000128788	ENSMUSP00000118015
ENSMUST00000137120
ENSMUST00000152016

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002046	opsin binding
GO:0005515	protein binding

Biological Process

GO:0001822	kidney development
GO:0007224	smoothened signaling pathway
GO:0008542	visual learning
GO:0022008	neurogenesis
GO:0034067	protein localization to Golgi apparatus
GO:0035845	photoreceptor cell outer segment organization
GO:0036372	opsin transport
GO:0042073	intraciliary transport
GO:0042384	cilium assembly
GO:0051642	centrosome localization
GO:0055007	cardiac muscle cell differentiation
GO:0060828	regulation of canonical Wnt signaling pathway
GO:0061351	neural precursor cell proliferation
GO:0061512	protein localization to cilium
GO:1902017	regulation of cilium assembly
GO:2000785	regulation of autophagic vacuole assembly

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005794	Golgi apparatus
GO:0005813	centrosome
GO:0005814	centriole
GO:0005929	cilium
GO:0030992	intraciliary transport particle B
GO:0031514	motile cilium
GO:0032391	photoreceptor connecting cilium
GO:0036064	ciliary basal body
GO:0044292	dendrite terminus
GO:0070062	extracellular vesicular exosome
GO:0072372	primary cilium
GO:0097546	ciliary base

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000109083

View Gene Order

ENSBTAG00000008110

Not yet available

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.358671 Mm.437824

RefSeq

NM_018854

OMIM

CCDS

CCDS25111

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas