Version 5.4
| Homo sapiens Gene: PLEKHG4 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-36574.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | PLEKHG4 | ||||||||||||||||||
| Gene Name | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | ||||||||||||||||||
| Synonyms | ARHGEF44; PRTPHN1; SCA4 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000196155 | ||||||||||||||||||
| Encoded Proteins |
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5\' UTR, or encoding a different isoform, have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 16:67277510-67289499 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q22.1 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||
| SwissProt | Q58EX7 | ||||||||||||||||||
| TrEMBL | A0A024R6X4 C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 25894 | ||||||||||||||||||
| UniGene | Hs.188781 Hs.614444 | ||||||||||||||||||
| RefSeq | NM_001129728 NM_001129727 NM_001129729 NM_001129731 NM_015432 | ||||||||||||||||||
| HUGO | HGNC:24501 | ||||||||||||||||||
| OMIM | 609526 | ||||||||||||||||||
| CCDS | CCDS32466 CCDS45512 | ||||||||||||||||||
| HPRD | 10890 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB197663 AB197664 AC040160 AK024475 AL117435 BC054486 BC063501 BC082974 CH471092 FJ905766 | ||||||||||||||||||
| GenPept | AAH54486 AAH63501 AAH82974 ACR15145 BAB15765 BAE07054 BAE07055 CAB55923 EAW83117 EAW83119 EAW83121 | ||||||||||||||||||
| RNA Seq Atlas | 25894 | ||||||||||||||||||