Homo sapiens Gene: PLEKHG4 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-36574.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | PLEKHG4 | ||||||||||||||||||
Gene Name | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | ||||||||||||||||||
Synonyms | ARHGEF44; PRTPHN1; SCA4 | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000196155 | ||||||||||||||||||
Encoded Proteins |
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5' UTR, or encoding a different isoform, have been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene contains multiple domains suggestive of a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Mutations in this gene are associated with spinocerebellar ataxia 16q22-linked. Several alternatively spliced transcript variants, differing only in the 5\' UTR, or encoding a different isoform, have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 16:67277510-67289499 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q22.1 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q58EX7 | ||||||||||||||||||
TrEMBL | A0A024R6X4 C5IFI8 H3BME5 H3BPQ5 H3BQE6 H3BQP9 H3BSU4 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 25894 | ||||||||||||||||||
UniGene | Hs.188781 Hs.614444 | ||||||||||||||||||
RefSeq | NM_001129728 NM_001129727 NM_001129729 NM_001129731 NM_015432 | ||||||||||||||||||
HUGO | HGNC:24501 | ||||||||||||||||||
OMIM | 609526 | ||||||||||||||||||
CCDS | CCDS32466 CCDS45512 | ||||||||||||||||||
HPRD | 10890 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AB197663 AB197664 AC040160 AK024475 AL117435 BC054486 BC063501 BC082974 CH471092 FJ905766 | ||||||||||||||||||
GenPept | AAH54486 AAH63501 AAH82974 ACR15145 BAB15765 BAE07054 BAE07055 CAB55923 EAW83117 EAW83119 EAW83121 | ||||||||||||||||||
RNA Seq Atlas | 25894 | ||||||||||||||||||