Homo sapiens Gene: DEFB127
Summary
InnateDB Gene IDBG-36658.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEFB127
Gene Name defensin, beta 127
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000088782
Encoded Proteins
defensin, beta 127
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:157470-159163
Strand Forward strand
Band p13
Transcripts
ENST00000382388 ENSP00000371825
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Defensins pathway
Innate Immune System pathway
Beta defensins pathway
Immune System pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9H1M4
TrEMBL
UniProt Splice Variant
Entrez Gene 140850
UniGene Hs.99362
RefSeq NM_139074
HUGO HGNC:16206
OMIM
CCDS CCDS12991
HPRD 10877
IMGT
EMBL AF525929 AL360078 AY122479 AY358796 BC069486 BC109395
GenPept AAH69486 AAI09396 AAM93920 AAP47222 AAQ89156 CAC17685
RNA Seq Atlas 140850