Version 5.4
Homo sapiens Protein: DEFB127
Summary
InnateDB Protein IDBP-36660.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DEFB127
Protein Name defensin, beta 127
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371825
InnateDB Gene IDBG-36658 (DEFB127)
Protein Structure
UniProt Annotation
Function Has antibacterial activity. {ECO:0000305}.
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0042742 defense response to bacterium
GO:0045087 innate immune response
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H1M4
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 140850
UniGene Hs.99362
RefSeq NP_620713
HUGO HGNC:16206
OMIM
CCDS CCDS12991
HPRD 10877
IMGT
EMBL AF525929 AL360078 AY122479 AY358796 BC069486 BC109395
GenPept AAH69486 AAI09396 AAM93920 AAP47222 AAQ89156 CAC17685

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca