Homo sapiens Gene: VPRBP
Summary
InnateDB Gene IDBG-37403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPRBP
Gene Name Vpr (HIV-1) binding protein
Synonyms DCAF1;
Species Homo sapiens
Ensembl Gene ENSG00000145041
Encoded Proteins
Vpr (HIV-1) binding protein
Vpr (HIV-1) binding protein
Vpr (HIV-1) binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:51395867-51500002
Strand Reverse strand
Band p21.2
Transcripts
ENST00000335891 ENSP00000338857
ENST00000423656 ENSP00000393183
ENST00000504652 ENSP00000421724
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.
Experimentally validated
Total 83 [view]
Protein-Protein 83 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:1990244 histone kinase activity (H2A-T120 specific)
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0030183 B cell differentiation
GO:0033151 V(D)J recombination
GO:0035212 cell competition in a multicellular organism
GO:1990245 histone H2A-T120 phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008180 COP9 signalosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Adaptive Immune System pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL D6RAK9 H0Y4P3
UniProt Splice Variant
Entrez Gene 9730
UniGene Hs.716623
RefSeq NM_014703 XM_005276751 XM_005276752 XM_005276753 XM_005276754 XM_005276755 XM_006713426 XM_006713427 NM_001171904
HUGO HGNC:30911
OMIM
CCDS CCDS74943 CCDS74944
HPRD 11674
IMGT
EMBL AB018343 AC092037 AF061935 AL080145 BC022792 BC110371
GenPept AAG27134 AAH22792 AAI10372 BAA34520 CAB45738
RNA Seq Atlas 9730