Version 5.4
Homo sapiens Gene: VPRBP
Summary
InnateDB Gene IDBG-37403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPRBP
Gene Name Vpr (HIV-1) binding protein
Synonyms DCAF1
Species Homo sapiens
Ensembl Gene ENSG00000145041
Encoded Proteins
IDBP-37407
Vpr (HIV-1) binding protein
IDBP-378706
Vpr (HIV-1) binding protein
IDBP-476701
Vpr (HIV-1) binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:51395867-51500002
Strand Reverse strand
Band p21.2
Transcripts
ENST00000335891 ENSP00000338857
ENST00000423656 ENSP00000393183
ENST00000504652 ENSP00000421724
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 83 experimentally validated interaction(s) in this database.
Experimentally validated
Total 83 [view]
Protein-Protein 83 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:1990244 histone kinase activity (H2A-T120 specific)
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0030183 B cell differentiation
GO:0033151 V(D)J recombination
GO:0035212 cell competition in a multicellular organism
GO:1990245 histone H2A-T120 phosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008180 COP9 signalosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040325
View Gene Order
ENSBTAG00000006501
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.716623
RefSeq NM_001171904 NM_014703 XM_005276751 XM_005276752 XM_005276753 XM_005276754 XM_005276755 XM_006713426 XM_006713427
HUGO
OMIM
CCDS CCDS74943 CCDS74944
HPRD 11674
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca