Version 5.4
Homo sapiens Gene: TRIM36
Summary
InnateDB Gene IDBG-37599.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM36
Gene Name tripartite motif containing 36
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000152503
Encoded Proteins
IDBP-37601
tripartite motif containing 36
IDBP-37603
tripartite motif containing 36
IDBP-37605
tripartite motif containing 36
IDBP-485318
tripartite motif containing 36
IDBP-473870
tripartite motif containing 36
IDBP-482392
tripartite motif containing 36
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23438823
TRIM36 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:115124762-115180546
Strand Reverse strand
Band q22.3
Transcripts
ENST00000282369 ENSP00000282369
ENST00000379618 ENSP00000368938
ENST00000379617 ENSP00000368937
ENST00000513154 ENSP00000423934
ENST00000514154 ENSP00000424259
ENST00000513485
ENST00000515104
ENST00000510222
ENST00000508894 ENSP00000424743
ENST00000511701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0007340 acrosome reaction
GO:0016567 protein ubiquitination
GO:0045087 innate immune response (InnateDB)
GO:0051726 regulation of cell cycle
Cellular Component
GO:0001669 acrosomal vesicle
GO:0005622 intracellular
GO:0005856 cytoskeleton
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033949
View Gene Order
ENSBTAG00000014027
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.519514 Hs.599403 Hs.624202
RefSeq NM_001017397 NM_001017398 NM_001300759 NM_018700 XM_005272031
HUGO
OMIM
CCDS CCDS34211 CCDS34212 CCDS4115 CCDS75287
HPRD 15554
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca