Version 5.4
Homo sapiens Gene: AP3S1
Summary
InnateDB Gene IDBG-37945.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AP3S1
Gene Name adaptor-related protein complex 3, sigma 1 subunit
Synonyms CLAPS3; Sigma3A
Species Homo sapiens
Ensembl Gene ENSG00000177879
Encoded Proteins
IDBP-37947
adaptor-related protein complex 3, sigma 1 subunit
IDBP-603908
adaptor-related protein complex 3, sigma 1 subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:115841481-115914081
Strand Forward strand
Band q22.3
Transcripts
ENST00000316788 ENSP00000325369
ENST00000395548
ENST00000514118
ENST00000515066
ENST00000509055
ENST00000507436
ENST00000505423
ENST00000506430 ENSP00000446179
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0008565 protein transporter activity
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0008089 anterograde axon cargo transport
GO:0008286 insulin receptor signaling pathway
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0048490 anterograde synaptic vesicle transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0030117 membrane coat
GO:0030119 AP-type membrane coat adaptor complex
GO:0030123 AP-3 adaptor complex
GO:0030133 transport vesicle
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000024480
View Gene Order
Pathways
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.662086 Hs.720978 Hs.740519
RefSeq NM_001284 XM_005271872
HUGO
OMIM
CCDS CCDS4123
HPRD 03298
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca