Version 5.4
Homo sapiens Gene: TAOK1
Summary
InnateDB Gene IDBG-38294.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAOK1
Gene Name TAO kinase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160551
Encoded Proteins
IDBP-38296
TAO kinase 1
IDBP-596959
TAO kinase 1
IDBP-758782
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:29390464-29551904
Strand Forward strand
Band q11.2
Transcripts
ENST00000261716 ENSP00000261716
ENST00000536202 ENSP00000438819
ENST00000578653
ENST00000577583
ENST00000583121 ENSP00000464562
ENST00000587277
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0000165 MAPK cascade
GO:0000186 activation of MAPKK activity
GO:0000278 mitotic cell cycle
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0031572 G2 DNA damage checkpoint
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0046330 positive regulation of JNK cascade
GO:0051493 regulation of cytoskeleton organization
GO:0097194 execution phase of apoptosis
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017291
View Gene Order
ENSBTAG00000000827
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
hsa04010
MAPK signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.597434 Hs.729236 Hs.735869
RefSeq NM_020791 NM_025142
HUGO
OMIM
CCDS CCDS32601 CCDS56024
HPRD 15467
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca