Version 5.4
Homo sapiens Gene: COMMD6
Summary
InnateDB Gene IDBG-38385.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COMMD6
Gene Name COMM domain containing 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188243
Encoded Proteins
IDBP-38387
COMM domain containing 6
IDBP-38389
COMM domain containing 6
IDBP-38391
COMM domain containing 6
IDBP-38393
COMM domain containing 6
IDBP-294278
COMM domain containing 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary COMMD6 belongs to a family of NF-kappa-B (see RELA; MIM 164014)-inhibiting proteins characterized by the presence of a COMM domain (see COMMD1; MIM 607238) (de Bie et al., 2006 [PubMed 16573520]).[supplied by OMIM, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:75525219-75549439
Strand Reverse strand
Band q22.2
Transcripts
ENST00000377619 ENSP00000366845
ENST00000377615 ENSP00000366841
ENST00000355801 ENSP00000348054
ENST00000377612 ENSP00000366838
ENST00000406936 ENSP00000385660
ENST00000486516
ENST00000483290
ENST00000460675
ENST00000497707
ENST00000464050
ENST00000477377
ENST00000471682
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051059 NF-kappaB binding
Biological Process
GO:0032088 negative regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075486
View Gene Order
ENSBTAG00000009824
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.713055
RefSeq NM_001287392 NM_001287393 NM_001287394 NM_203495 NM_203497 XM_006719769
HUGO
OMIM
CCDS CCDS9451 CCDS9452
HPRD 13084
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca