Version 5.4
Homo sapiens Gene: SNTB2
Summary
InnateDB Gene IDBG-38937.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNTB2
Gene Name syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Synonyms D16S2531E; EST25263; SNT2B2; SNT3; SNTL
Species Homo sapiens
Ensembl Gene ENSG00000168807
Encoded Proteins
IDBP-38939
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
IDBP-38941
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
IDBP-600587
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
IDBP-746707
IDBP-585434
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:69187129-69309052
Strand Forward strand
Band q22.1
Transcripts
ENST00000336278 ENSP00000338191
ENST00000360496 ENSP00000353686
ENST00000467311 ENSP00000436443
ENST00000524887 ENSP00000462765
ENST00000525632 ENSP00000432201
ENST00000528525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0044822 poly(A) RNA binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016020 membrane
GO:0030054 cell junction
GO:0030658 transport vesicle membrane
GO:0043234 protein complex
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041308
View Gene Order
ENSBTAG00000001654
Not yet available
Cross-References
SwissProt Q13425
TrEMBL
UniProt Splice Variant
Entrez Gene 6645
UniGene Hs.461117 Hs.645751 Hs.717683
RefSeq NM_006750 XM_005256120
HUGO HGNC:11169
OMIM 600027
CCDS CCDS10873
HPRD 02491
IMGT
EMBL AF243385 BC048215 U40572
GenPept AAC50449 AAH48215 AAK15149
RNA Seq Atlas 6645

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca