Homo sapiens Gene: SNTB2
Summary
InnateDB Gene IDBG-38937.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNTB2
Gene Name syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Synonyms D16S2531E; EST25263; SNT2B2; SNT3; SNTL;
Species Homo sapiens
Ensembl Gene ENSG00000168807
Encoded Proteins
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:69187129-69309052
Strand Forward strand
Band q22.1
Transcripts
ENST00000336278 ENSP00000338191
ENST00000360496 ENSP00000353686
ENST00000467311 ENSP00000436443
ENST00000524887 ENSP00000462765
ENST00000525632 ENSP00000432201
ENST00000528525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 24 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 24 [view]
Protein-Protein 23 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0044822 poly(A) RNA binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016020 membrane
GO:0030054 cell junction
GO:0030658 transport vesicle membrane
GO:0043234 protein complex
GO:0045202 synapse
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.461117 Hs.645751 Hs.717683
RefSeq NM_006750 XM_005256120
HUGO
OMIM
CCDS CCDS10873
HPRD 02491
IMGT
EMBL
GenPept
RNA Seq Atlas