Homo sapiens Gene: SCEL
Summary
InnateDB Gene IDBG-40000.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCEL
Gene Name sciellin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000136155
Encoded Proteins
sciellin
sciellin
sciellin
sciellin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:77535674-77645263
Strand Forward strand
Band q22.3
Transcripts
ENST00000349847 ENSP00000302579
ENST00000377246 ENSP00000366454
ENST00000471491 ENSP00000432840
ENST00000469982
ENST00000535157 ENSP00000437895
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0008544 epidermis development
GO:0009790 embryo development
GO:0030216 keratinocyte differentiation
Cellular Component
GO:0001533 cornified envelope
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt O95171
TrEMBL
UniProt Splice Variant
Entrez Gene 8796
UniGene Hs.534699 Hs.591224
RefSeq NM_144777 NM_003843 NM_001160706
HUGO HGNC:10573
OMIM 604112
CCDS CCDS9459 CCDS9458 CCDS53877
HPRD 09161
IMGT
EMBL AF045941 AK222720 AK301659 AL137140 BC047536 CH471093
GenPept AAC78461 AAH47536 BAD96440 BAH13533 CAH70475 CAH70476 EAW80568 EAW80569
RNA Seq Atlas 8796