Homo sapiens Gene: LSM6
Summary
InnateDB Gene IDBG-40113.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSM6
Gene Name LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Synonyms YDR378C;
Species Homo sapiens
Ensembl Gene ENSG00000164167
Encoded Proteins
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:146175685-146200000
Strand Forward strand
Band q31.22
Transcripts
ENST00000296581 ENSP00000296581
ENST00000515311 ENSP00000427036
ENST00000503982
ENST00000502781 ENSP00000422392
ENST00000504181 ENSP00000420929
ENST00000510331
ENST00000507449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006364 rRNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
Cellular Component
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0030532 small nuclear ribonucleoprotein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
mRNA decay by 5' to 3' exoribonuclease pathway
Deadenylation-dependent mRNA decay pathway
Gene Expression pathway
KEGG
RNA degradation pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.190520
RefSeq NM_007080
HUGO
OMIM
CCDS CCDS3767
HPRD 06286
IMGT
EMBL
GenPept
RNA Seq Atlas