Homo sapiens Gene: SCARF2
Summary
InnateDB Gene IDBG-401942.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCARF2
Gene Name scavenger receptor class F, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000244486
Encoded Proteins
scavenger receptor class F, member 2
scavenger receptor class F, member 2
scavenger receptor class F, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20424585-20437859
Strand Reverse strand
Band q11.21
Transcripts
ENST00000494535
ENST00000622235 ENSP00000477564
ENST00000623402 ENSP00000485276
ENST00000615031 ENSP00000479389
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0007157 heterophilic cell-cell adhesion
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.474251
RefSeq NM_153334 NM_182895
HUGO
OMIM
CCDS CCDS46666
HPRD 15299
IMGT
EMBL
GenPept
RNA Seq Atlas