Version 5.4
Homo sapiens Gene: ARHGAP10
Summary
InnateDB Gene IDBG-40526.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGAP10
Gene Name Rho GTPase activating protein 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000071205
Encoded Proteins
IDBP-40528
Rho GTPase activating protein 10
IDBP-475755
Rho GTPase activating protein 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:147732063-148072780
Strand Forward strand
Band q31.23
Transcripts
ENST00000336498 ENSP00000336923
ENST00000510379
ENST00000506054
ENST00000507661 ENSP00000422358
ENST00000506020
ENST00000513548
ENST00000510076
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0007010 cytoskeleton organization
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0032321 positive regulation of Rho GTPase activity
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037148
View Gene Order
ENSBTAG00000002531
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_13528
Regulation of PAK-2p34 activity by PS-GAP/RHG10 pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_578
Apoptosis pathway
REACT_111102
Signal Transduction pathway
REACT_13648
Regulation of Apoptosis pathway
KEGG
hsa05100
Bacterial invasion of epithelial cells pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.368631 Hs.600129
RefSeq NM_024605 XM_005263216 XM_005263217
HUGO
OMIM
CCDS CCDS34075
HPRD 07949
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca