Version 5.4
Homo sapiens Gene: NAT6
Summary
InnateDB Gene IDBG-409138.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAT6
Gene Name N-acetyltransferase 6 (GCN5-related)
Synonyms FUS-2; FUS2
Species Homo sapiens
Ensembl Gene ENSG00000243477
Encoded Proteins
IDBP-36316
N-acetyltransferase 6 (GCN5-related)
IDBP-378197
N-acetyltransferase 6 (GCN5-related)
IDBP-378198
N-acetyltransferase 6 (GCN5-related)
IDBP-378199
N-acetyltransferase 6 (GCN5-related)
IDBP-378201
N-acetyltransferase 6 (GCN5-related)
IDBP-378202
N-acetyltransferase 6 (GCN5-related)
IDBP-378204
N-acetyltransferase 6 (GCN5-related)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:50296402-50299421
Strand Reverse strand
Band p21.31
Transcripts
ENST00000354862 ENSP00000346927
ENST00000417393 ENSP00000391893
ENST00000443094 ENSP00000410610
ENST00000443842 ENSP00000400559
ENST00000450489 ENSP00000388316
ENST00000442620 ENSP00000391158
ENST00000452674 ENSP00000413623
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008080 N-acetyltransferase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000079334
View Gene Order
ENSBTAG00000038084
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001200016 NM_001200018 NM_012191
HUGO
OMIM
CCDS CCDS43095 CCDS56258
HPRD 06148
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca