Homo sapiens Gene: NAT6
Summary
InnateDB Gene IDBG-409138.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAT6
Gene Name N-acetyltransferase 6 (GCN5-related)
Synonyms FUS-2; FUS2;
Species Homo sapiens
Ensembl Gene ENSG00000243477
Encoded Proteins
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
N-acetyltransferase 6 (GCN5-related)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the N-acetyltransferase family. N-acetyltransferases modify proteins by transferring acetyl groups from acetyl CoA to the N-termini of protein substrates. The encoded protein is a cytoplasmic N-acetyltransferase with a substrate specificity for proteins with an N-terminal methionine. This gene is located in the tumor suppressor gene region on chromosome 3p21.3 and the encoded protein may play a role in cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed. This gene overlaps and is on the same strand as hyaluronoglucosaminidase 3, and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:50296402-50299421
Strand Reverse strand
Band p21.31
Transcripts
ENST00000354862 ENSP00000346927
ENST00000417393 ENSP00000391893
ENST00000443094 ENSP00000410610
ENST00000443842 ENSP00000400559
ENST00000450489 ENSP00000388316
ENST00000442620 ENSP00000391158
ENST00000452674 ENSP00000413623
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008080 N-acetyltransferase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q93015
TrEMBL C9J451 C9JL88 Q6IAP1
UniProt Splice Variant
Entrez Gene 24142
UniGene
RefSeq NM_001200016 NM_001200018 NM_012191
HUGO HGNC:30252
OMIM 607073
CCDS CCDS56258 CCDS43095
HPRD 06148
IMGT
EMBL AF040705 AF040706 AK313803 BC004483 CH471055 CR457113 U73167
GenPept AAC02732 AAC70912 AAC70913 AAH04483 BAG36539 CAG33394 EAW65077 EAW65078 EAW65080 EAW65081 EAW65082
RNA Seq Atlas 24142