Homo sapiens Protein: NAT6
Summary
InnateDB Protein IDBP-36316.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NAT6
Protein Name N-acetyltransferase 6 (GCN5-related)
Synonyms FUS-2; FUS2;
Species Homo sapiens
Ensembl Protein ENSP00000346927
InnateDB Gene IDBG-409138 (NAT6)
Protein Structure
UniProt Annotation
Function Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. {ECO:0000269PubMed:10644992}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:10644992}.
Disease Associations
Tissue Specificity Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0008080 N-acetyltransferase activity
GO:0008415 acyltransferase activity
GO:0016740 transferase activity
Biological Process
GO:0008152 metabolic process
GO:0045786 negative regulation of cell cycle
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000182 GNAT domain
IPR016181 Acyl-CoA N-acyltransferase
PFAM PF00583
PF13302
PF13508
PF13673
PF13718
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q93015
PhosphoSite PhosphoSite-Q93015
TrEMBL Q6IAP1
UniProt Splice Variant
Entrez Gene 24142
UniGene
RefSeq NP_036323
HUGO HGNC:30252
OMIM 607073
CCDS CCDS43095
HPRD 06148
IMGT
EMBL AF040705 AF040706 AK313803 BC004483 CH471055 CR457113 U73167
GenPept AAC02732 AAC70912 AAC70913 AAH04483 BAG36539 CAG33394 EAW65077 EAW65078 EAW65080 EAW65081 EAW65082