Version 5.4
Homo sapiens Gene: CPA1
Summary
InnateDB Gene IDBG-41337.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPA1
Gene Name carboxypeptidase A1 (pancreatic)
Synonyms CPA
Species Homo sapiens
Ensembl Gene ENSG00000091704
Encoded Proteins
IDBP-41339
carboxypeptidase A1 (pancreatic)
IDBP-483136
carboxypeptidase A1 (pancreatic)
IDBP-477337
carboxypeptidase A1 (pancreatic)
IDBP-479927
carboxypeptidase A1 (pancreatic)
IDBP-810950
carboxypeptidase A1 (pancreatic)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:130380339-130388114
Strand Forward strand
Band q32.2
Transcripts
ENST00000011292 ENSP00000011292
ENST00000481342 ENSP00000420218
ENST00000491460
ENST00000476062 ENSP00000419408
ENST00000484324 ENSP00000419497
ENST00000470838
ENST00000479106
ENST00000478096
ENST00000604896 ENSP00000475021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004181 metallocarboxypeptidase activity
GO:0008238 exopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054446
View Gene Order
ENSBTAG00000046169
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04972
Pancreatic secretion pathway
hsa04974
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9JQ63
UniProt Splice Variant
Entrez Gene 1357
UniGene Hs.2879 Hs.610928
RefSeq NM_001868
HUGO HGNC:2296
OMIM 114850
CCDS CCDS5820
HPRD 00269
IMGT
EMBL AC007938
GenPept
RNA Seq Atlas 1357

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca