InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: PTGES3

Summary

InnateDB Gene

IDBG-41485.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTGES3

Gene Name

prostaglandin E synthase 3 (cytosolic)

Synonyms

cPGES; P23; TEBP

Species

Homo sapiens

Ensembl Gene

ENSG00000110958

Encoded Proteins

IDBP-41487

prostaglandin E synthase 3 (cytosolic)

IDBP-378184

prostaglandin E synthase 3 (cytosolic)

IDBP-378185

prostaglandin E synthase 3 (cytosolic)

IDBP-378187

prostaglandin E synthase 3 (cytosolic)

IDBP-378188

prostaglandin E synthase 3 (cytosolic)

IDBP-810770

prostaglandin E synthase 3 (cytosolic)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:56663341-56688408

Strand

Reverse strand

Band

q13.3

Transcripts

ENST00000262033	ENSP00000262033
ENST00000456859	ENSP00000389090
ENST00000436399	ENSP00000402385
ENST00000414274	ENSP00000405299
ENST00000448157	ENSP00000414892
ENST00000537473
ENST00000614328	ENSP00000482075

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	97 [view]
Protein-Protein	93 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003720	telomerase activity
GO:0005515	protein binding
GO:0050220	prostaglandin-E synthase activity
GO:0051082	unfolded protein binding

Biological Process

GO:0000723	telomere maintenance
GO:0001516	prostaglandin biosynthetic process
GO:0005978	glycogen biosynthetic process
GO:0006278	RNA-dependent DNA replication
GO:0007165	signal transduction
GO:0008283	cell proliferation
GO:0019369	arachidonic acid metabolic process
GO:0019371	cyclooxygenase pathway
GO:0042921	glucocorticoid receptor signaling pathway
GO:0043588	skin development
GO:0044281	small molecule metabolic process
GO:0060430	lung saccule development
GO:0070389	chaperone cofactor-dependent protein refolding

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0005697	telomerase holoenzyme complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome