InnateDB Protein
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IDBP-41487.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PTGES3
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Protein Name
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prostaglandin E synthase 3 (cytosolic)
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Synonyms
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cPGES; P23; TEBP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000262033
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InnateDB Gene
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IDBG-41485 (PTGES3)
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Protein Structure
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Function |
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. {ECO:0000269PubMed:10922363, ECO:0000269PubMed:11274138, ECO:0000269PubMed:12077419}.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
97
[view]
|
Protein-Protein |
93
[view]
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Protein-DNA |
4
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007052
CS domain
IPR008978
HSP20-like chaperone
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PFAM |
PF04969
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q15185
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PhosphoSite |
PhosphoSite-Q15185
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TrEMBL |
A0A024RB32
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UniProt Splice Variant |
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Entrez Gene |
10728
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UniGene |
Hs.739520
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RefSeq |
NP_006592
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HUGO |
HGNC:16049
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OMIM |
607061
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CCDS |
CCDS31836
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HPRD |
06138
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IMGT |
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EMBL |
AC117378
AK291945
AK295208
AK298147
AK298160
BC003005
BC021167
CH471054
L24804
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GenPept |
AAA18537
AAH03005
AAH21167
BAF84634
BAG58204
BAG60423
BAG60433
EAW96953
EAW96956
EAW96957
EAW96958
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