Homo sapiens Gene: RGS9BP
Summary
InnateDB Gene IDBG-42264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS9BP
Gene Name regulator of G protein signaling 9 binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186326
Encoded Proteins
regulator of G protein signaling 9 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32675407-32678300
Strand Forward strand
Band q13.11
Transcripts
ENST00000334176 ENSP00000334134
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007603 phototransduction, visible light
GO:0009968 negative regulation of signal transduction
GO:0016056 rhodopsin mediated signaling pathway
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0050908 detection of light stimulus involved in visual perception
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
The phototransduction cascade pathway
Inactivation, recovery and regulation of the phototransduction cascade pathway
Disease pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Visual signal transduction: Cones
Visual signal transduction: Rods
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.528491
RefSeq NM_207391
HUGO
OMIM
CCDS CCDS12424
HPRD 16991
IMGT
EMBL
GenPept
RNA Seq Atlas