Homo sapiens Gene: DUSP18 | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-4294.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | DUSP18 | ||||||||||
Gene Name | dual specificity phosphatase 18 | ||||||||||
Synonyms | |||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Gene | ENSG00000167065 | ||||||||||
Encoded Proteins |
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
dual specificity phosphatase 18
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 22:30652051-30667890 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | q12.2 | ||||||||||
Transcripts | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | F8VX42 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 150290 | ||||||||||
UniGene | Hs.517544 Hs.680453 | ||||||||||
RefSeq | NM_152511 XM_005261367 | ||||||||||
HUGO | HGNC:18484 | ||||||||||
OMIM | 611446 | ||||||||||
CCDS | CCDS13883 | ||||||||||
HPRD | 13253 | ||||||||||
IMGT | |||||||||||
EMBL | AC003072 AC005006 | ||||||||||
GenPept | |||||||||||
RNA Seq Atlas | 150290 | ||||||||||