Version 5.4
Homo sapiens Gene: UGGT2
Summary
InnateDB Gene IDBG-43209.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UGGT2
Gene Name UDP-glucose glycoprotein glucosyltransferase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102595
Encoded Proteins
IDBP-43211
UDP-glucose glycoprotein glucosyltransferase 2
IDBP-43217
UDP-glucose glycoprotein glucosyltransferase 2
IDBP-43219
UDP-glucose glycoprotein glucosyltransferase 2
IDBP-234931
UDP-glucose glycoprotein glucosyltransferase 2
IDBP-812955
UDP-glucose glycoprotein glucosyltransferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:95801580-96053482
Strand Reverse strand
Band q32.1
Transcripts
ENST00000376747 ENSP00000365938
ENST00000376714 ENSP00000365904
ENST00000376712 ENSP00000365902
ENST00000397618 ENSP00000380743
ENST00000462472
ENST00000476866
ENST00000491509
ENST00000463054
ENST00000465196
ENST00000461329
ENST00000467305
ENST00000621375 ENSP00000482021
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
GO:0016757 transferase activity, transferring glycosyl groups
Biological Process
GO:0006457 protein folding
GO:0006486 protein glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0097359 UDP-glucosylation
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042104
View Gene Order
ENSBTAG00000004401
Not yet available
Pathways
NETPATH
REACTOME
REACT_25091
ER Quality Control Compartment (ERQC) pathway
REACT_23810
Calnexin/calreticulin cycle pathway
REACT_23878
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q9NYU1
TrEMBL A6NP03 E7EMU6 Q08AC9 Q8N5K0
UniProt Splice Variant
Entrez Gene 55757
UniGene Hs.193226
RefSeq NM_020121
HUGO HGNC:15664
OMIM 605898
CCDS CCDS9480
HPRD
IMGT
EMBL AF227906 AL133051 AL136104 AL158192 AL162500 AL607038 BC032302 BC125233 BC125234
GenPept AAF66233 AAH32302 AAI25234 AAI25235 CAB61378 CAH72447 CAI13708 CAI39962 CAI40146
RNA Seq Atlas 55757

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca