Version 5.4
Homo sapiens Gene: RAP2A
Summary
InnateDB Gene IDBG-43996.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAP2A
Gene Name RAP2A, member of RAS oncogene family
Synonyms K-REV; KREV; RAP2; RbBP-30
Species Homo sapiens
Ensembl Gene ENSG00000125249
Encoded Proteins
IDBP-43998
RAP2A, member of RAS oncogene family
IDBP-597305
RAP2A, member of RAS oncogene family
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:97434222-97469128
Strand Forward strand
Band q32.1
Transcripts
ENST00000245304 ENSP00000245304
ENST00000476869 ENSP00000436462
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0030336 negative regulation of cell migration
GO:0031532 actin cytoskeleton reorganization
GO:0031954 positive regulation of protein autophosphorylation
GO:0032486 Rap protein signal transduction
GO:0034613 cellular protein localization
GO:0045184 establishment of protein localization
GO:0046328 regulation of JNK cascade
GO:0048814 regulation of dendrite morphogenesis
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016020 membrane
GO:0030496 midbody
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051615
View Gene Order
ENSBTAG00000020412
Not yet available
Pathways
NETPATH
NetPath_12
BCR pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6U784
UniProt Splice Variant
Entrez Gene 5911
UniGene Hs.508480 Hs.598577
RefSeq NM_021033
HUGO HGNC:9861
OMIM 179540
CCDS CCDS9485
HPRD 01547
IMGT
EMBL AL442067
GenPept
RNA Seq Atlas 5911

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca