Homo sapiens Gene: SSBP1
Summary
InnateDB Gene IDBG-44535.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSBP1
Gene Name single-stranded DNA binding protein 1, mitochondrial
Synonyms Mt-SSB; mtSSB; SOSS-B1; SSBP;
Species Homo sapiens
Ensembl Gene ENSG00000106028
Encoded Proteins
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1
single-stranded DNA binding protein 1, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141738321-141787922
Strand Forward strand
Band q34
Transcripts
ENST00000265304 ENSP00000265304
ENST00000496622
ENST00000498107 ENSP00000419541
ENST00000489378
ENST00000469123
ENST00000467681 ENSP00000418068
ENST00000465582 ENSP00000420485
ENST00000461433
ENST00000463093 ENSP00000419579
ENST00000465167
ENST00000468267
ENST00000484178 ENSP00000419388
ENST00000473783 ENSP00000418181
ENST00000481508 ENSP00000419665
ENST00000612337 ENSP00000480488
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
Experimentally validated
Total 91 [view]
Protein-Protein 90 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006260 DNA replication
GO:0051096 positive regulation of helicase activity
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial biogenesis pathway
Transcriptional activation of mitochondrial biogenesis pathway
KEGG
DNA replication pathway
Mismatch repair pathway
Homologous recombination pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.490394 Hs.740496
RefSeq NM_001256510 NM_001256511 NM_001256512 NM_001256513 NM_003143 XM_005250049 XM_005250050
HUGO
OMIM
CCDS CCDS5866
HPRD 02703
IMGT
EMBL
GenPept
RNA Seq Atlas