Version 5.4
Homo sapiens Gene: SSBP1
Summary
InnateDB Gene IDBG-44535.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SSBP1
Gene Name single-stranded DNA binding protein 1, mitochondrial
Synonyms Mt-SSB; mtSSB; SOSS-B1; SSBP
Species Homo sapiens
Ensembl Gene ENSG00000106028
Encoded Proteins
IDBP-44537
single-stranded DNA binding protein 1
IDBP-473545
single-stranded DNA binding protein 1
IDBP-479559
single-stranded DNA binding protein 1
IDBP-483946
single-stranded DNA binding protein 1
IDBP-481043
single-stranded DNA binding protein 1
IDBP-485020
single-stranded DNA binding protein 1
IDBP-481776
single-stranded DNA binding protein 1
IDBP-481940
single-stranded DNA binding protein 1
IDBP-811078
single-stranded DNA binding protein 1, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:141738321-141787922
Strand Forward strand
Band q34
Transcripts
ENST00000265304 ENSP00000265304
ENST00000496622
ENST00000498107 ENSP00000419541
ENST00000489378
ENST00000469123
ENST00000467681 ENSP00000418068
ENST00000465582 ENSP00000420485
ENST00000461433
ENST00000463093 ENSP00000419579
ENST00000465167
ENST00000468267
ENST00000484178 ENSP00000419388
ENST00000473783 ENSP00000418181
ENST00000481508 ENSP00000419665
ENST00000612337 ENSP00000480488
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 91 experimentally validated interaction(s) in this database.
Experimentally validated
Total 91 [view]
Protein-Protein 90 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006260 DNA replication
GO:0051096 positive regulation of helicase activity
GO:0070584 mitochondrion morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029911
View Gene Order
ENSBTAG00000010931
Not yet available
Pathways
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_200788
Mitochondrial biogenesis pathway
REACT_200608
Transcriptional activation of mitochondrial biogenesis pathway
KEGG
hsa03030
DNA replication pathway
hsa03440
Homologous recombination pathway
hsa03430
Mismatch repair pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9J8J0 C9K0U8 E7EUY5
UniProt Splice Variant
Entrez Gene 6742
UniGene Hs.490394 Hs.740496
RefSeq XM_005250050 NM_001256510 NM_001256511 NM_001256512 NM_001256513 NM_003143 XM_005250049
HUGO HGNC:11317
OMIM 600439
CCDS CCDS5866
HPRD 02703
IMGT
EMBL AC004918 AC004979
GenPept
RNA Seq Atlas 6742

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca