Homo sapiens Gene: ADAM29
Summary
InnateDB Gene IDBG-45123.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM29
Gene Name ADAM metallopeptidase domain 29
Synonyms CT73; svph1;
Species Homo sapiens
Ensembl Gene ENSG00000168594
Encoded Proteins
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
ADAM metallopeptidase domain 29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:174829668-174978180
Strand Forward strand
Band q34.1
Transcripts
ENST00000359240 ENSP00000352177
ENST00000404450 ENSP00000384229
ENST00000445694 ENSP00000414544
ENST00000507652
ENST00000507969
ENST00000513477
ENST00000505141 ENSP00000427370
ENST00000502940 ENSP00000427674
ENST00000502305 ENSP00000422537
ENST00000510280
ENST00000515538
ENST00000514159 ENSP00000423517
ENST00000615367 ENSP00000484862
ENST00000618444 ENSP00000478469
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007283 spermatogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL D6RBU0 D6RHU0
UniProt Splice Variant
Entrez Gene 11086
UniGene
RefSeq NM_001278125 XM_005262704 NM_014269 NM_001278126 NM_001130704 NM_001130705 NM_001130703 NM_001278127 XM_005262705
HUGO HGNC:207
OMIM 604778
CCDS CCDS3823
HPRD
IMGT
EMBL AC093868 AC105914 AF134708 AF171929 AF171930 AF171931 AK292410 CH471056
GenPept AAF03777 AAF03778 AAF03779 AAF22163 AAY41055 BAF85099 EAX04727 EAX04728
RNA Seq Atlas 101928551 102725164 11086