Version 5.4
Homo sapiens Gene: ADAM29
Summary
InnateDB Gene IDBG-45123.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAM29
Gene Name ADAM metallopeptidase domain 29
Synonyms CT73; svph1
Species Homo sapiens
Ensembl Gene ENSG00000168594
Encoded Proteins
IDBP-45125
ADAM metallopeptidase domain 29
IDBP-294968
ADAM metallopeptidase domain 29
IDBP-379869
ADAM metallopeptidase domain 29
IDBP-480290
ADAM metallopeptidase domain 29
IDBP-473756
ADAM metallopeptidase domain 29
IDBP-479858
ADAM metallopeptidase domain 29
IDBP-473983
ADAM metallopeptidase domain 29
IDBP-807650
ADAM metallopeptidase domain 29
IDBP-807652
ADAM metallopeptidase domain 29
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:174829668-174978180
Strand Forward strand
Band q34.1
Transcripts
ENST00000359240 ENSP00000352177
ENST00000404450 ENSP00000384229
ENST00000445694 ENSP00000414544
ENST00000507652
ENST00000507969
ENST00000513477
ENST00000505141 ENSP00000427370
ENST00000502940 ENSP00000427674
ENST00000502305 ENSP00000422537
ENST00000510280
ENST00000515538
ENST00000514159 ENSP00000423517
ENST00000615367 ENSP00000484862
ENST00000618444 ENSP00000478469
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0007283 spermatogenesis
Cellular Component
GO:0005887 integral component of plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q9UKF5
TrEMBL D6RBU0 D6RHU0
UniProt Splice Variant
Entrez Gene 11086
UniGene Hs.126838 Hs.721287
RefSeq NM_001130703 NM_001130704 NM_001130705 NM_001278125 NM_001278126 NM_001278127 NM_014269 XM_005262704 XM_005262705
HUGO HGNC:207
OMIM 604778
CCDS CCDS3823
HPRD
IMGT
EMBL AC093868 AC105914 AF134708 AF171929 AF171930 AF171931 AK292410 CH471056
GenPept AAF03777 AAF03778 AAF03779 AAF22163 AAY41055 BAF85099 EAX04727 EAX04728
RNA Seq Atlas 101928551 102725164 11086

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca