Homo sapiens Gene: KCNV2
Summary
InnateDB Gene IDBG-45135.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNV2
Gene Name potassium channel, subfamily V, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168263
Encoded Proteins
potassium channel, subfamily V, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:2717502-2730037
Strand Forward strand
Band p24.2
Transcripts
ENST00000382082 ENSP00000371514
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005251 delayed rectifier potassium channel activity
Biological Process
GO:0006811 ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Neuronal System pathway
Voltage gated Potassium channels pathway
Potassium Channels pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8TDN2
TrEMBL
UniProt Splice Variant
Entrez Gene 169522
UniGene Hs.622675
RefSeq NM_133497
HUGO HGNC:19698
OMIM 607604
CCDS CCDS6447
HPRD
IMGT
EMBL AF348983 AL354723 BC101352 BC101353
GenPept AAI01353 AAI01354 AAL83910 CAI15124
RNA Seq Atlas 169522