Homo sapiens Gene: TM9SF2
Summary
InnateDB Gene IDBG-46230.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TM9SF2
Gene Name transmembrane 9 superfamily member 2
Synonyms P76;
Species Homo sapiens
Ensembl Gene ENSG00000125304
Encoded Proteins
transmembrane 9 superfamily member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:99501417-99564006
Strand Forward strand
Band q32.3
Transcripts
ENST00000376387 ENSP00000365567
ENST00000463709
ENST00000466555
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 10 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
Cellular Component
GO:0005768 endosome
GO:0005887 integral component of plasma membrane
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q99805
TrEMBL A0A024QYR8
UniProt Splice Variant
Entrez Gene 9375
UniGene Hs.629172 Hs.654824
RefSeq NM_004800
HUGO HGNC:11865
OMIM 604678
CCDS CCDS9493
HPRD 09198
IMGT
EMBL AK290514 AL139035 BC110656 BC130293 BK008790 CH471085 U81006
GenPept AAB38973 AAI10657 AAI30294 BAF83203 CAH71381 DAA64545 EAX09023
RNA Seq Atlas 9375