InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TM9SF2

Summary

InnateDB Protein

IDBP-46232.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TM9SF2

Protein Name

transmembrane 9 superfamily member 2

Synonyms

P76;

Species

Homo sapiens

Ensembl Protein

ENSP00000365567

InnateDB Gene

IDBG-46230 (TM9SF2)

Protein Structure

UniProt Annotation

Function

In the intracellular compartments, may function as a channel or small molecule transporter.

Subcellular Localization

Endosome membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Ubiquitously expressed. Especially abundant in pancreas, highly expressed in kidney, lower levels in heart, brain, skeletal muscle and placenta. Lowest expression in lung and liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	10 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0006810

transport

Cellular Component

GO:0005768	endosome
GO:0005887	integral component of plasma membrane
GO:0010008	endosome membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome