Version 5.4
Homo sapiens Gene: PITRM1
Summary
InnateDB Gene IDBG-46405.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PITRM1
Gene Name pitrilysin metallopeptidase 1
Synonyms MP1; PreP
Species Homo sapiens
Ensembl Gene ENSG00000107959
Encoded Proteins
IDBP-46407
pitrilysin metallopeptidase 1
IDBP-46409
pitrilysin metallopeptidase 1
IDBP-46411
pitrilysin metallopeptidase 1
IDBP-362625
pitrilysin metallopeptidase 1
IDBP-362638
pitrilysin metallopeptidase 1
IDBP-362641
pitrilysin metallopeptidase 1
IDBP-362667
pitrilysin metallopeptidase 1
IDBP-362671
pitrilysin metallopeptidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:3137728-3172841
Strand Reverse strand
Band p15.2
Transcripts
ENST00000224949 ENSP00000224949
ENST00000380994 ENSP00000370382
ENST00000380989 ENSP00000370377
ENST00000451104 ENSP00000401201
ENST00000455371 ENSP00000399307
ENST00000451454 ENSP00000413687
ENST00000424714 ENSP00000402072
ENST00000430362 ENSP00000391526
ENST00000490510
ENST00000464395
ENST00000488065
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004222 metalloendopeptidase activity
GO:0008047 enzyme activator activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021193
View Gene Order
ENSBTAG00000002685
Not yet available
Cross-References
SwissProt Q5JRX3
TrEMBL
UniProt Splice Variant
Entrez Gene 10531
UniGene
RefSeq NM_001242309 XM_005252345 NM_001242307 NM_014889 XM_006717362
HUGO HGNC:17663
OMIM
CCDS CCDS55700 CCDS55699 CCDS59208
HPRD 07142
IMGT
EMBL AB029027 AF061243 AK002061 AK303406 AL451164 BC001150 BC005025 BC095422 BC111987 BC113369
GenPept AAC67244 AAH01150 AAH05025 AAH95422 AAI11988 AAI13370 BAA83056 BAG51008 BAG64460 CAI39997 CAI40001
RNA Seq Atlas 10531

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca