InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PITRM1

Summary

InnateDB Protein

IDBP-362625.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PITRM1

Protein Name

pitrilysin metallopeptidase 1

Synonyms

MP1; PreP;

Species

Homo sapiens

Ensembl Protein

ENSP00000401201

InnateDB Gene

IDBG-46405 (PITRM1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004222	metalloendopeptidase activity
GO:0008047	enzyme activator activity
GO:0046872	metal ion binding

Biological Process

GO:0006508	proteolysis
GO:0043085	positive regulation of catalytic activity

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR007863 Peptidase M16, C-terminal domain
IPR011249 Metalloenzyme, LuxS/M16 peptidase-like
IPR011765 Peptidase M16, N-terminal
IPR013578 Peptidase M16C associated

PFAM

PF05193
PF00675
PF08367

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5JRX3

PhosphoSite