Version 5.4
Homo sapiens Gene: NME5
Summary
InnateDB Gene IDBG-46521.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NME5
Gene Name NME/NM23 family member 5
Synonyms NM23-H5; NM23H5; RSPH23
Species Homo sapiens
Ensembl Gene ENSG00000112981
Encoded Proteins
IDBP-46523
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138115172-138139443
Strand Reverse strand
Band q31.2
Transcripts
ENST00000265191 ENSP00000265191
ENST00000506657
ENST00000514481
ENST00000508252
ENST00000511353
ENST00000512954
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
Biological Process
GO:0003351 epithelial cilium movement
GO:0006165 nucleoside diphosphate phosphorylation
GO:0006183 GTP biosynthetic process
GO:0006228 UTP biosynthetic process
GO:0006241 CTP biosynthetic process
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0009116 nucleoside metabolic process
GO:0021591 ventricular system development
GO:0042384 cilium assembly
GO:0048515 spermatid differentiation
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Cellular Component
GO:0005575 cellular_component
GO:0036126 sperm flagellum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035984
View Gene Order
ENSBTAG00000008752
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Folate metabolism pathway
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.730856
RefSeq NM_003551 XM_005272098
HUGO
OMIM
CCDS CCDS4197
HPRD 04655
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca