Homo sapiens Gene: AK3
Summary
InnateDB Gene IDBG-46603.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AK3
Gene Name adenylate kinase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147853
Encoded Proteins
adenylate kinase 3
adenylate kinase 3
adenylate kinase 3
adenylate kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:4709559-4742043
Strand Reverse strand
Band p24.1
Transcripts
ENST00000381809 ENSP00000371230
ENST00000359883 ENSP00000352948
ENST00000447596 ENSP00000413933
ENST00000611749 ENSP00000482308
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0046899 nucleoside triphosphate adenylate kinase activity
Biological Process
GO:0006172 ADP biosynthetic process
GO:0007596 blood coagulation
GO:0016310 phosphorylation
GO:0046033 AMP metabolic process
GO:0046039 GTP metabolic process
GO:0046041 ITP metabolic process
GO:0046051 UTP metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Factors involved in megakaryocyte development and platelet production pathway
Hemostasis pathway
KEGG
Purine metabolism pathway
INOH
Pyrimidine nucleotides nucleosides metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9UIJ7
TrEMBL
UniProt Splice Variant
Entrez Gene 50808
UniGene Hs.590590 Hs.732022
RefSeq NM_001199852 NM_001199853 NM_001199855 NM_001199856 NM_016282
HUGO HGNC:17376
OMIM 609290
CCDS CCDS56562 CCDS56561 CCDS6455
HPRD 12439
IMGT
EMBL AB021870 AF183419 AK001553 AK001951 AK027534 AK098205 AK298200 AL136231 AL353151 BC013771 CH471071
GenPept AAG09688 AAH13771 BAA87913 BAA91753 BAA91996 BAB55183 BAG53592 BAG60470 CAH72282 CAH72283 CAI41260 CAI41262 EAW58779 EAW58780 EAW58781
RNA Seq Atlas 50808